Title : Combination Therapy With Rapamycin and Low Dose Imatinib in Pulmonary Hypertension.

Pub. Date : 2021

PMID : 34858182






1 Functional Relationships(s)
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1 Methods and Results: Immunoblotting analyses revealed that short-term exposure to rapamycin (6h) significantly reduced phosphorylation of p70S6K (mTORC1-specific) in hPASMCs but had no effect on the phosphorylation of AKT (p-AKT S473, considered mTORC2-specific). Sirolimus ribosomal protein S6 kinase B1 Homo sapiens