Title : Failure to EGFR-TKI-based therapy and tumoural progression are promoted by MEOX2/GLI1-mediated epigenetic regulation of EGFR in the human lung cancer.

Pub. Date : 2022 Jan

PMID : 34844838






1 Functional Relationships(s)
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1 In addition, MEOX2/GLI1 was shown to be involved in the increased proliferation of tumour cells and resistance capacity to cisplatin, EGFR-TKIs (erlotinib and AZD9291 "osimertinib"), AZD8542-SMO, and AZD6244-MEKK1/2. Erlotinib Hydrochloride GLI family zinc finger 1 Homo sapiens