Title : WSF-CT-11, a Sesquiterpene Derivative, Activates AMP-Activated Protein Kinase with Anti-diabetic Effects in 3T3-L1 Adipocytes.

Pub. Date : 2021 Nov 23

PMID : 34841171






2 Functional Relationships(s)
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1 Synthetic sesquiterpene derivatives were investigated to identify novel AMPK activators as anti-diabetic drugs because the leading drugs like metformin and thiazolidinediones (TZDs) activate AMPK by inhibiting the synthesis of adenosine 5"-triphosphate and thus are associated with some side effects. Adenosine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 Synthetic sesquiterpene derivatives were investigated to identify novel AMPK activators as anti-diabetic drugs because the leading drugs like metformin and thiazolidinediones (TZDs) activate AMPK by inhibiting the synthesis of adenosine 5"-triphosphate and thus are associated with some side effects. Adenosine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens