Title : PAX-D: study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression.

Pub. Date : 2022 May

PMID : 34810175






1 Functional Relationships(s)
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1 Previous small randomised controlled trials suggested that pramipexole, a dopamine D2/3 receptor agonist, may be effective for treating patients with unipolar and bipolar depression as it is known to influence motivational drive and reward processing. Pramipexole dopamine receptor D2 Homo sapiens