Title : Silencing lncRNA NEAT1 reduces nonalcoholic fatty liver fat deposition by regulating the miR-139-5p/c-Jun/SREBP-1c pathway.

Pub. Date : 2022 Mar-Apr

PMID : 34808393






1 Functional Relationships(s)
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1 CONCLUSION: NEAT1 aggravated FFA-induced lipid accumulation in hepatocytes by regulating the c-Jun/SREBP1c axis by sponging miR-139-5p, indicating the potential of NEAT1 as a promising therapeutic target for NAFLD. Fatty Acids, Nonesterified sterol regulatory element binding transcription factor 1 Homo sapiens