Title : Modulatory role of atorvastatin against high-fat diet and zymosan-induced activation of TLR2/NF-ƙB signaling pathway in C57BL/6 mice.

Pub. Date : 2021 Aug

PMID : 34804419






2 Functional Relationships(s)
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1 Results: Atorvastatin treatment along with HFD and Zym inhibited vascular inflammation by suppressing the levels of aortic TLR2, cardiac NF-kB and decrease in serum TNF-alpha and IL-6. Atorvastatin interleukin 6 Mus musculus
2 Conclusion: Atorvastatin attenuates vascular inflammation mediated by HFD and Zym through suppression of TLR2, NF-kB, TNF-alpha, IL-6, and upregulation of LDLR levels. Atorvastatin interleukin 6 Mus musculus