Title : In vitro and in silico characterization of adiponectin-receptor agonist dipeptides.

Pub. Date : 2021 Nov 12

PMID : 34772952






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tyr-Pro induces glucose transporter 4 (Glut4) expression in the plasma membrane, along with adenosine monophosphate-activated protein kinase (AMPK) activation. tyrosyl-proline protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 Tyr-Pro induces glucose transporter 4 (Glut4) expression in the plasma membrane, along with adenosine monophosphate-activated protein kinase (AMPK) activation. tyrosyl-proline protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
3 In AdipoR1-knocked down cells, the promotion by Tyr-Pro was ameliorated, indicating that Tyr-Pro may directly interact with AdipoR1 as an agonist, followed by the activation of AMPK/Glut4 translocation in L6 myotubes. tyrosyl-proline protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
4 In AdipoR1-knocked down cells, the promotion by Tyr-Pro was ameliorated, indicating that Tyr-Pro may directly interact with AdipoR1 as an agonist, followed by the activation of AMPK/Glut4 translocation in L6 myotubes. tyrosyl-proline protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens