Title : Effect of Epigallocatechin-3-Gallate on EGFR Signaling and Migration in Non-Small Cell Lung Cancer.

Pub. Date : 2021 Oct 31

PMID : 34769263






5 Functional Relationships(s)
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1 Effect of Epigallocatechin-3-Gallate on EGFR Signaling and Migration in Non-Small Cell Lung Cancer. epigallocatechin gallate epidermal growth factor receptor Homo sapiens
2 Epigallocatechin-3-gallate (EGCG), the main bioactive molecule in green tea, acts as a tyrosine kinase inhibitor toward cancer cells overexpressing EGFR (wild-type). epigallocatechin gallate epidermal growth factor receptor Homo sapiens
3 Epigallocatechin-3-gallate (EGCG), the main bioactive molecule in green tea, acts as a tyrosine kinase inhibitor toward cancer cells overexpressing EGFR (wild-type). epigallocatechin gallate epidermal growth factor receptor Homo sapiens
4 However, little information has been reported on the effect of EGCG on EGFR with activating mutations. epigallocatechin gallate epidermal growth factor receptor Homo sapiens
5 In this study, we evaluated the ability of EGCG to inhibit EGFR signaling activation in three different NSCLC cell lines containing wild-type EGFR or EGFR with additional mutations. epigallocatechin gallate epidermal growth factor receptor Homo sapiens