Title : Combination of the Glutaminyl Cyclase Inhibitor PQ912 (Varoglutamstat) and the Murine Monoclonal Antibody PBD-C06 (m6) Shows Additive Effects on Brain Aβ Pathology in Transgenic Mice.

Pub. Date : 2021 Oct 30

PMID : 34769222






1 Functional Relationships(s)
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1 Compelling evidence suggests that pyroglutamate-modified Abeta (pGlu3-Abeta; AbetaN3pG) peptides play a pivotal role in the development and progression of Alzheimer"s disease (AD). Pyrrolidonecarboxylic Acid amyloid beta (A4) precursor protein Mus musculus