Pub. Date : 2021 Nov
PMID : 34748530
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death. | NAD | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 2 | In conclusion, hyperactivation of PARP1 in response to ROS-induced DNA damage, fueled by NAMPT-derived NAD+, mediates skin inflammation through parthanatos cell death. | NAD | poly(ADP-ribose) polymerase 1 | Homo sapiens |