Title : Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis.

Pub. Date : 2021 Nov 2

PMID : 34731617






1 Functional Relationships(s)
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1 LivePAR, a genetically encoded probe for live-cell imaging of poly(ADP-ribose) (PAR), reveals that Polbeta and XRCC1 require PAR for repair-complex assembly, with PARP1 and PARP2 playing unique roles in complex dynamics. Poly Adenosine Diphosphate Ribose X-ray repair cross complementing 1 Homo sapiens