Title : Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis.

Pub. Date : 2021 Nov 2

PMID : 34731617






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis. NAD poly(ADP-ribose) polymerase 1 Homo sapiens
2 These findings highlight coordinated yet independent roles for PARP1, PARP2, and SIRT6 and their regulation by NAD+ bioavailability to facilitate BER. NAD poly(ADP-ribose) polymerase 1 Homo sapiens