Title : Hypoglycemia possibly caused by CYP2C9-mediated drug interaction in combination with bucolome: a case report.

Pub. Date : 2021 Nov 3

PMID : 34727989






2 Functional Relationships(s)
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1 CONCLUSIONS: Based on the clinical course and literature review, we believe that hypoglycemia in the present case was due to a drug interaction, caused by inhibition of CYP2C9 by bucolome and competitive inhibition of CYP2C9 by warfarin, which affected the pharmacokinetics of glimepiride. glimepiride cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 CONCLUSIONS: Based on the clinical course and literature review, we believe that hypoglycemia in the present case was due to a drug interaction, caused by inhibition of CYP2C9 by bucolome and competitive inhibition of CYP2C9 by warfarin, which affected the pharmacokinetics of glimepiride. glimepiride cytochrome P450 family 2 subfamily C member 9 Homo sapiens