Title : β2-Adrenoceptor Activation Stimulates IL-6 Production via PKA, ERK1/2, Src, and Beta-Arrestin2 Signaling Pathways in Human Bronchial Epithelia.

Pub. Date : 2021 Dec

PMID : 34725715






3 Functional Relationships(s)
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1 We previously reported that isoprenaline, via the apical and basolateral beta2-adrenoceptor, induced Cl- secretion by activating cyclic AMP (cAMP)-dependent pathways in human bronchial epithelia. Cyclic AMP adrenoceptor beta 2 Homo sapiens
2 We previously reported that isoprenaline, via the apical and basolateral beta2-adrenoceptor, induced Cl- secretion by activating cyclic AMP (cAMP)-dependent pathways in human bronchial epithelia. Cyclic AMP adrenoceptor beta 2 Homo sapiens
3 Despite these results, whether and how the beta2-adrenoceptor-mediated cAMP-dependent pathway contributes to pro-inflammatory cytokine release in human bronchial epithelia remains poorly understood. Cyclic AMP adrenoceptor beta 2 Homo sapiens