Title : Transforming growth factor-β1 decreases erythropoietin production through repressing hypoxia-inducible factor 2α in erythropoietin-producing cells.

Pub. Date : 2021 Nov 2

PMID : 34724959






1 Functional Relationships(s)
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1 However, TGF-beta1 repressed HIF2alpha-encoding Epas1 promptly through activating activin receptor-like kinase-5 (ALK5), thereby decreasing Epo induction by hypoxia and prolyl hydroxylase domain inhibitor roxadustat. roxadustat transforming growth factor, beta 1 Mus musculus