Title : A novel lncRNA ROPM-mediated lipid metabolism governs breast cancer stem cell properties.

Pub. Date : 2021 Oct 29

PMID : 34715882






1 Functional Relationships(s)
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1 The increased PLA2G16 significantly promotes phospholipid metabolism and the production of free fatty acid, especially arachidonic acid in BCSCs, thereby activating PI3K/AKT, Wnt/beta-catenin, and Hippo/YAP signaling, thus eventually involving in the maintenance of BCSCs stemness. Fatty Acids, Nonesterified AKT serine/threonine kinase 1 Homo sapiens