Title : Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes.

Pub. Date : 2022 Feb

PMID : 34709423






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Functional assays demonstrated that Treg-mediated suppression of CD4+ effector T cells from slow progressors was significantly impaired, compared with healthy donors. treg CD4 molecule Homo sapiens
2 However, effector CD4+ T cells from slow progressors were more responsive to Treg suppression compared with healthy donors, demonstrated by increased suppression of CD25 and CD134 expression on effector CD4+ T cells. treg CD4 molecule Homo sapiens
3 However, effector CD4+ T cells from slow progressors were more responsive to Treg suppression compared with healthy donors, demonstrated by increased suppression of CD25 and CD134 expression on effector CD4+ T cells. treg CD4 molecule Homo sapiens