Title : Synergistic and additive interactions between receptor signaling networks drive the regulatory T cell versus T helper 17 cell fate choice.

Pub. Date : 2021 Dec

PMID : 34688667






1 Functional Relationships(s)
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1 These data provide a biochemical mechanism by which CD4+ T cells integrate TCR, TGF-beta, and IL-6 signals via generation of alternate SMAD3 complexes that control the development of early signaling networks to potentiate the choice of Treg versus Th17 cell fate. treg interleukin 6 Homo sapiens