Title : Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity.

Pub. Date : 2022 Feb 24

PMID : 34665619






1 Functional Relationships(s)
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1 PLpro is a promising therapeutic target, albeit challenging owing to featureless P1 and P2 sites recognizing glycine. Glycine ORF1a polyprotein;ORF1ab polyprotein Severe acute respiratory syndrome coronavirus 2