Pub. Date : 2021 Nov 2
PMID : 34662099
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For example, the replacement of the glutamic acid side with a glycine chain at position 305 in the CYP17A1 structure causes a clinically relevant steroidopathy; E305G CYP17A1 displays a dramatic decrease in the production of dehydroepiandrosterone from pregnenolone but surprisingly increases the activity of the enzyme toward the formation of androstenedione from progesterone. | Androstenedione | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | For example, the replacement of the glutamic acid side with a glycine chain at position 305 in the CYP17A1 structure causes a clinically relevant steroidopathy; E305G CYP17A1 displays a dramatic decrease in the production of dehydroepiandrosterone from pregnenolone but surprisingly increases the activity of the enzyme toward the formation of androstenedione from progesterone. | Androstenedione | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |