Title : m6A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin.

Pub. Date : 2021 Oct 17

PMID : 34657574






3 Functional Relationships(s)
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1 In this study, it was found that SQSTM1/p62 (sequestosome 1), an autophagy receptor, was significantly downregulated in two human keratinocyte cells lines with short-term high-glucose treatment, as well as in the epidermis of diabetic patients and a db/db mouse model with long-term hyperglycemia. Glucose sequestosome 1 Homo sapiens
2 In this study, it was found that SQSTM1/p62 (sequestosome 1), an autophagy receptor, was significantly downregulated in two human keratinocyte cells lines with short-term high-glucose treatment, as well as in the epidermis of diabetic patients and a db/db mouse model with long-term hyperglycemia. Glucose sequestosome 1 Homo sapiens
3 In this study, it was found that SQSTM1/p62 (sequestosome 1), an autophagy receptor, was significantly downregulated in two human keratinocyte cells lines with short-term high-glucose treatment, as well as in the epidermis of diabetic patients and a db/db mouse model with long-term hyperglycemia. Glucose sequestosome 1 Homo sapiens