Title : Transcriptional regulation of chorionic gonadotropin alpha- and beta-subunit gene expression by 8-bromo-adenosine 3',5'-monophosphate.

Pub. Date : 1986 Dec

PMID : 3465528






2 Functional Relationships(s)
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Protein Name
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1 In placental explants and cell lines, cAMP stimulates the biosynthesis of CG alpha- and beta-subunits and produces marked stimulation of CG secretion. Cyclic AMP chromogranin A Homo sapiens
2 RNA blot hybridization analysis demonstrated that 8-Br-cAMP increased CG alpha and beta mRNA levels 15- to 30-fold, consistent with 8-Br-cAMP regulation of CG biosynthesis at a pretranslational level. Cyclic AMP chromogranin A Homo sapiens