Protein Name chromogranin A
Organism Homo sapiens
Gene ID 1113
Gene Symbol


UniProt P10645 (CMGA_HUMAN), G5E968 (G5E968_HUMAN), Q86T07 (Q86T07_HUMAN)
Relationships Total Number of functionally related compound(s) : 758
Total Number of Articles : 951

chromogranin A

Gene Summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

  • chromogranin-A
  • SP-I
  • betagranin (N-terminal fragment of chromogranin A)
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