Title : Mafenide derivatives inhibit neuroinflammation in Alzheimer's disease by regulating pyroptosis.

Pub. Date : 2021 Nov

PMID : 34632701






1 Functional Relationships(s)
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1 As a result, the administration of Sulfa-4 and Sulfa-22 could significantly inhibit the activation of microglia, decrease the expression of inflammatory factors in the central nervous system and simultaneously suppress the production of p30-GSDMD as well as the expression of upstream NLRP3 inflammasome and Caspase-1 protein. sulfa-22 NLR family, pyrin domain containing 3 Mus musculus