Title : Effects of isoflavone derivatives on the production of inflammatory cytokines by synovial cells.

Pub. Date : 2021 Nov

PMID : 34630655






2 Functional Relationships(s)
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1 Daidzein significantly inhibited the phosphorylation of NF-kappaB p65 and ERK1/2, but not p38 MAPK in IL-1beta-stimulated MH7A cells. daidzein mitogen-activated protein kinase 3 Homo sapiens
2 The present study revealed that among the isoflavone derivatives examined (daidzein, genistein and glycitein), daidzein inhibited the production of IL-6, but not IL-8, by IL-1beta-stimulated synovial MH7A cells via the suppression of NF-kappaB p65 and ERK1/2 activation. daidzein mitogen-activated protein kinase 3 Homo sapiens