Title : Metformin Protects Against Inflammation, Oxidative Stress to Delay Poly I:C-Induced Aging-Like Phenomena in the Gut of an Annual Fish.

Pub. Date : 2022 Feb 3

PMID : 34626114






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1 The results of q-PCR analysis showed that metformin reduced NF-kappaB mediated inflammatory response including decreased level of pro-inflammatory cytokine IL-8 and increased expression of anti-inflammatory cytokine IL-10 in gut of the fish with natural aging and poly I:C-injected 6-month-old fish. Metformin interleukin 10 Homo sapiens