Pub. Date : 2021 Dec
PMID : 34620548
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, both TP and TP-nanolip-PEG suppressed the polarization of M2 macrophages and downregulated gene expressions of TGF-beta1, Smad 2, Smad 3, alpha-SMA, and collagen I (p < 0.05), but upregulated the gene expression of E-cadherin (p < 0.05), thus reversing TGF-beta1 induced EMT/EndoMT and attenuating subretinal fibrosis. | triptolide | transforming growth factor, beta 1 | Mus musculus |
| 2 | Moreover, both TP and TP-nanolip-PEG suppressed the polarization of M2 macrophages and downregulated gene expressions of TGF-beta1, Smad 2, Smad 3, alpha-SMA, and collagen I (p < 0.05), but upregulated the gene expression of E-cadherin (p < 0.05), thus reversing TGF-beta1 induced EMT/EndoMT and attenuating subretinal fibrosis. | triptolide | transforming growth factor, beta 1 | Mus musculus |
| 3 | Moreover, both TP and TP-nanolip-PEG suppressed the polarization of M2 macrophages and downregulated gene expressions of TGF-beta1, Smad 2, Smad 3, alpha-SMA, and collagen I (p < 0.05), but upregulated the gene expression of E-cadherin (p < 0.05), thus reversing TGF-beta1 induced EMT/EndoMT and attenuating subretinal fibrosis. | triptolide | transforming growth factor, beta 1 | Mus musculus |
| 4 | Moreover, both TP and TP-nanolip-PEG suppressed the polarization of M2 macrophages and downregulated gene expressions of TGF-beta1, Smad 2, Smad 3, alpha-SMA, and collagen I (p < 0.05), but upregulated the gene expression of E-cadherin (p < 0.05), thus reversing TGF-beta1 induced EMT/EndoMT and attenuating subretinal fibrosis. | triptolide | transforming growth factor, beta 1 | Mus musculus |