Pub. Date : 2021 Nov
PMID : 34619149
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Autophagic degradation of IRF3 induced by the small molecule auranofin inhibits its transcriptional and pro-apoptotic activities. | Auranofin | interferon regulatory factor 3 | Homo sapiens |
| 2 | We conducted a high throughput screen, which identified auranofin as a small-molecule inhibitor of the pro-apoptotic activity of IRF3. | Auranofin | interferon regulatory factor 3 | Homo sapiens |
| 3 | In addition to the non-transcriptional apoptotic pathway, auranofin also inhibited the transcriptional activity of IRF3. | Auranofin | interferon regulatory factor 3 | Homo sapiens |