Pub. Date : 2021 Oct
PMID : 34612084
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Relevance of NR1I2 variants on carbamazepine therapy in Mexican Mestizos with epilepsy at a tertiary-care hospital. | Carbamazepine | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 2 | Results: CBZ response was associated with NR1I2 variants and lamotrigine cotreatment. | Carbamazepine | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 3 | CBZ plasma concentrations were influenced by NR1I2-rs2276707 and -rs3814058, and by phenytoin cotreatment. | Carbamazepine | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 4 | CBZ daily dose was also influenced by NR1I2-rs3814055 and EPHX1-rs1051740. | Carbamazepine | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 5 | Conclusion: Interindividual variability in CBZ treatment was partly explained by NR1I2, EPHX1 and SCN1A variants, as well as antiepileptic cotreatment in MM with epilepsy. | Carbamazepine | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |