Title : Knockdown of LKB1 Sensitizes Endometrial Cancer Cells via AMPK Activation.

Pub. Date : 2021 Nov 1

PMID : 34607979






1 Functional Relationships(s)
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1 Metformin diminished the phosphorylation of mTOR, p70S6K and 4E-BP1 by accelerating adenosine monophosphateactivated kinase (AMPK) in HeLa cancer cells, but it did not affect other cell lines. Metformin mechanistic target of rapamycin kinase Homo sapiens