Pub. Date : 2021 Dec
PMID : 34592660
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release. | Calcium | inositol 1,4,5-trisphosphate receptor type 3 | Homo sapiens |
| 2 | Moreover, MBL deficiency led to enhanced activation of the PERK-C/EBP-homologous protein (CHOP) pathway and initiates an inositol 1,4,5-trisphosphate receptor (IP3R)-mediated calcium release from the ER, thereby aggravating the hepatic ER stress response. | Calcium | inositol 1,4,5-trisphosphate receptor type 3 | Homo sapiens |