Title : Alisporivir Improves Mitochondrial Function in Skeletal Muscle of mdx Mice but Suppresses Mitochondrial Dynamics and Biogenesis.

Pub. Date : 2021 Sep 10

PMID : 34575944






1 Functional Relationships(s)
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1 At the same time, alisporivir suppressed mitochondrial biogenesis, assessed by the expression of Ppargc1a, and altered the dynamics of organelles, inhibiting both DRP1-mediated fission and MFN2-associated fusion of mitochondria. alisporivir peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus