Title : 3-methyadenine inhibits lipopolysaccharides-induced pulmonary inflammation at the early stage of silicosis via blocking NF-κB signaling pathway.

Pub. Date : 2021 Nov

PMID : 34565256






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1 The results showed that LPS induced NF-kappaB-related pulmonary inflammation in observers and silicosis patients, as confirmed by an increase in the expression of IL-1beta, IL-6, TNF-alpha, and p65, which could be inhibited by 3-MA treatment. 3-methyladenine interleukin 1 alpha Homo sapiens