Title : Cardio-protective effect of tetrahydrocurcumin, the primary hydrogenated metabolite of curcumin in vivo and in vitro: Induction of apoptosis and autophagy via PI3K/AKT/mTOR pathways.

Pub. Date : 2021 Nov 15

PMID : 34555398






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1 However, these effects on H9c2 cells were notably abolished by the PI3K inhibitor LY294002 and mTOR inhibitor rapamycin. Sirolimus mechanistic target of rapamycin kinase Rattus norvegicus