Title : Upregulation of UGT1A1 expression by ursolic acid and oleanolic acid via the inhibition of the PKC/NF-κB signaling pathway.

Pub. Date : 2021 Nov

PMID : 34536821






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Phorbol 12-myristate 13-acetate (PMA) and lipopolysaccharide (LPS), the agonists of PKC and NF-kappaB signaling, respectively, significantly inhibit hp65-mediated UGT1A1 luciferase activity. Tetradecanoylphorbol Acetate UDP glucuronosyltransferase family 1 member A1 Homo sapiens
2 Phorbol 12-myristate 13-acetate (PMA) and lipopolysaccharide (LPS), the agonists of PKC and NF-kappaB signaling, respectively, significantly inhibit hp65-mediated UGT1A1 luciferase activity. Tetradecanoylphorbol Acetate UDP glucuronosyltransferase family 1 member A1 Homo sapiens
3 PMA and LPS do not affect UGT1A1 activity in p65-silenced HepG2 cells; however, UA and OA mildly influence UGT1A1 expression in these cells. Tetradecanoylphorbol Acetate UDP glucuronosyltransferase family 1 member A1 Homo sapiens