Title : The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme.

Pub. Date : 2021 Sep 14

PMID : 34522028






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1 Retinoid-based multimodal differentiation therapy is one of the few interventions that extends relapse-free survival in MYCN-associated high-risk neuroblastoma and these results point toward the potential use of verlindamycin in this regimen. Retinoids MYCN proto-oncogene, bHLH transcription factor Homo sapiens