Protein Name | glutamate ionotropic receptor NMDA type subunit 1 |
---|---|
Organism | Homo sapiens |
Gene ID | 2902 |
Gene Symbol | GRIN1 |
UniProt | Q05586 (NMDZ1_HUMAN), Q59GW0 (Q59GW0_HUMAN), Q5VSF9 (Q5VSF9_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
332
Total Number of Articles : 589 |
Description |
glutamate ionotropic receptor NMDA type subunit 1 |
Gene Summary |
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] |
synonyms |
|
Properties | |