Protein Name glutamate ionotropic receptor NMDA type subunit 1
Organism Homo sapiens
Gene ID 2902
Gene Symbol

GRIN1

UniProt Q05586 (NMDZ1_HUMAN), Q59GW0 (Q59GW0_HUMAN), Q5VSF9 (Q5VSF9_HUMAN)
Relationships Total Number of functionally related compound(s) : 332
Total Number of Articles : 589
Description

glutamate ionotropic receptor NMDA type subunit 1

Gene Summary

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

synonyms
  • glutamate receptor ionotropic, NMDA 1
  • N-methyl-D-aspartate receptor channel, subunit zeta-1
  • N-methyl-D-aspartate receptor subunit NR1
Click to show/hide the synonyms
Properties