Title : Dipeptidyl peptidase-4 (DPP4) inhibitor sitagliptin alleviates liver inflammation of diabetic mice by acting as a ROS scavenger and inhibiting the NFκB pathway.

Pub. Date : 2021 Sep 7

PMID : 34493714






1 Functional Relationships(s)
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1 Moreover, sitagliptin reduced TNFalpha or LPS-induced cellular reactive oxygen species (ROS) level, cell apoptosis, and protein expression in the NFkappaB signaling pathway in HepG2 cells or primary mouse hepatocytes. Sitagliptin Phosphate nuclear factor kappa B subunit 1 Homo sapiens