Title : Crosstalk between protein kinase A and the HOG pathway under impaired biosynthesis of complex sphingolipids in budding yeast.

Pub. Date : 2022 Feb

PMID : 34492172






1 Functional Relationships(s)
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1 We also identified PBS2 encoding MAPKK in the high-osmolarity glycerol (HOG) pathway as a multicopy suppressor gene that rescues the hypersensitivity to AUR1 repression caused by deletion of IRA2, which causes hyperactivation of the cAMP/PKA pathway. Glycerol mitogen-activated protein kinase kinase PBS2 Saccharomyces cerevisiae S288C