Title : Vitiligo, alkaptonuria, and nitisinone-A report of three families and review of the literature.

Pub. Date : 2021 Sep

PMID : 34485014






1 Functional Relationships(s)
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1 Four patients, from three families, with alkaptonuria receiving 4-hydroxyphenylpyruvate dioxygenase-inhibiting nitisinone therapy, which lowers homogentisic acid and increases tyrosine, developed vitiligo. Tyrosine 4-hydroxyphenylpyruvate dioxygenase Homo sapiens