| Protein Name | 4-hydroxyphenylpyruvate dioxygenase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3242 |
| Gene Symbol | HPD |
| UniProt | P32754 (HPPD_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
113
Total Number of Articles : 98 |
Description |
4-hydroxyphenylpyruvate dioxygenase |
| Gene Summary |
The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] |
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| Properties | |