Title : Altered binding avidities and improved growth inhibitory effects of novel anti-HER3 mAb against human cancers in the presence of HER1-or HER2-targeted drugs.

Pub. Date : 2021 Oct 22

PMID : 34482024






1 Functional Relationships(s)
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1 A high KA by Ab6 and Ab6-mediated increased anti-proliferative effects against NCI-H1838 or BT474 were also respectively observed in the presence of Erlotinib (HER1 inhibitor) or Lapatinib (HER1/HER2 inhibitor). Lapatinib epidermal growth factor receptor Homo sapiens