Title : Design, synthesis and molecular docking of new [1,2,4] triazolo[4,3-a]quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase.

Pub. Date : 2021 Aug 30

PMID : 34460053






1 Functional Relationships(s)
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1 Such derivative showed the best VEGFR-2 inhibitory activity with an IC50 value of 3.9 nM, which is very close to that of sorafenib (IC50 = 3.13 nM). Sorafenib kinase insert domain receptor Homo sapiens