Title : APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation.

Pub. Date : 2021 Sep 14

PMID : 34450034






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Abeta generation. Cholesterol amyloid beta precursor protein Homo sapiens
2 Our study reveals the contribution of ApoE4 astrocytes to amyloidosis in neurons by expanding lipid rafts and facilitating Abeta production through an oversupply of cholesterol. Cholesterol amyloid beta precursor protein Homo sapiens