Title : DNA binding and evaluation of anticancer activity in vitro and in vivo of iridium(III) polypyridyl complexes.

Pub. Date : 2021 Nov

PMID : 34438219






1 Functional Relationships(s)
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1 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method was used to detect the cytotoxic activity of Ir1, Ir2 and Ir3, the complexes show highly active against B16 cells with IC50 values of 0.3 +- 0.2 muM, 3.7 +- 0.2 muM and 4.6 +- 1.1 muM, respectively. thiazolyl blue nischarin Homo sapiens