Pub. Date : 2021 Sep
PMID : 34433968
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans. | Heparitin Sulfate | TNF superfamily member 13 | Homo sapiens |
| 2 | Mechanistically, we demonstrate that APRIL confers atheroprotection by binding to heparan sulfate chains of heparan-sulfate proteoglycan 2 (HSPG2), which limits the retention of low-density lipoproteins, accumulation of macrophages and formation of necrotic cores. | Heparitin Sulfate | TNF superfamily member 13 | Homo sapiens |