Title : Impact of genetic and non-genetic factors on hepatic CYP2C9 expression and activity in Hungarian subjects.

Pub. Date : 2021 Aug 24

PMID : 34429480






1 Functional Relationships(s)
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1 The presence of CYP2C9*3 allele was associated with CYP2C9 functional impairment, and CYP2C9*2 influenced tolbutamide 4"-hydroxylase activity only in subjects with two polymorphic alleles, whereas the contribution of CYP2C8*3 was not confirmed. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens