Pub. Date : 2021
PMID : 34428765
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Celastrol Exerts Cardioprotective Effect in Rheumatoid Arthritis by Inhibiting TLR2/HMGB1 Signaling Pathway-Mediated Autophagy. | celastrol | high mobility group box 1 | Rattus norvegicus |
| 2 | RA induced cell autophagy can be suppressed by Celastrol through inhibiting the activation of TLR2/HMGB1 signal pathway. | celastrol | high mobility group box 1 | Rattus norvegicus |
| 3 | CONCLUSION: Celastrol can regulate TLR2/HMGB1 signal pathway to suppress autophagy and therefore exert cardioprotective effect in RA. | celastrol | high mobility group box 1 | Rattus norvegicus |