Pub. Date : 2021
PMID : 34422216
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole-Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway. | carveol | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |
| 2 | Furthermore, carveol treatment positively modulated the antioxidant gene Nrf2 and its downstream target HO-1. | carveol | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |
| 3 | Taken together, our findings suggest that carveol acts as an Nrf2 activator and therefore induces downstream antioxidants and mitigates inflammatory insults through multiple pathways. | carveol | NFE2 like bZIP transcription factor 2 | Rattus norvegicus |