Pub. Date : 2021
PMID : 34422067
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, docetaxel injection increased levels of TNF-alpha and IL-6 in plasma and expressions of phospho-NF-kappaB and phospho-STAT3 in both of lumbar spinal cord and sciatic nerves, while SH003 treatment inhibited those changes. | Docetaxel | tumor necrosis factor | Mus musculus |
| 2 | Taken together, it is worth noting that TNF-alpha and IL-6 in plasma and phospho-NF-kappaB and phospho-STAT3 in spinal cord and sciatic nerves are putative biomarkers of docetaxel-induced peripheral neuropathy (DIPN) in mouse models. | Docetaxel | tumor necrosis factor | Mus musculus |